Asymmetric hydrogenation of α- or β-acyloxy α,β-unsaturated phosphonates catalyzed by a Rh(I) complex of monodentate phosphoramidite.
نویسندگان
چکیده
The Rh(I) complex of a monodentate phosphoramidite bearing a primary amine moiety (DpenPhos) has been disclosed to be highly efficient for the asymmetric hydrogenation of a variety of α- or β-acyloxy α,β-unsaturated phosphonates, providing the corresponding biologically important chiral α- or β-hydroxy phosphonic acid derivatives with excellent enantioselectivities (90->99% ee).
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 10 8 شماره
صفحات -
تاریخ انتشار 2012